Atypical endometrial hyperplasia (AEH), also called endometrial intraepithelial neoplasia (EIN), is a condition in which the cells of the uterine lining (endometrium) grow abnormally and show precancerous changes.

AEH is not the same as endometrial cancer, but it is considered a precancerous condition because it carries a significant risk of progressing to cancer. In some patients, an early endometrial cancer may already be present when AEH is diagnosed, which is why proper evaluation and follow-up with a gynecologist are essential.

Possible symptoms include:
• Irregular or prolonged periods
• Heavy menstrual bleeding
• Bleeding between periods
• Postmenopausal bleeding
• Difficulty conceiving in some patients

Treatment depends on age, medical history, and fertility goals. Hysterectomy is the definitive treatment. For selected patients who wish to preserve fertility, progesterone-based treatment with careful endometrial monitoring and repeat biopsies may be considered under specialist supervision.

If future pregnancy is important, fertility planning should be discussed early as part of the treatment plan.