A semen analysis measures sperm count, movement (motility) and shape (morphology). It does not directly assess the integrity of the genetic material inside sperm.

What is sperm DNA fragmentation?

It refers to breaks in the DNA carried within sperm. Specialized tests assess this damage, providing information beyond a routine semen analysis. Normal semen results do not necessarily rule out increased DNA fragmentation.

Can it affect fertility?

Higher fragmentation has been associated with difficulty conceiving and an increased risk of pregnancy loss. However, an elevated result does not mean pregnancy is impossible or prove the cause of a miscarriage.

Who should consider testing?

Testing is not routinely recommended as part of an initial fertility evaluation. A specialist may recommend it in selected situations, such as recurrent pregnancy loss.

What are the limitations?

Testing methods and reference ranges differ. A result cannot reliably predict an individual couple’s pregnancy outcome and should be interpreted alongside both partners’ medical history and other findings.

Speak with your fertility specialist or reproductive urologist about whether testing would help guide your care.

Longevity Fertility Centre | Calgary & Edmonton